Estrogenic impact on cardiac ischemic/reperfusion injury

S Sivasinprasasn, K Shinlapawittayatorn… - Journal of …, 2016 - Springer
… team involving estrogen-deprived female rats demonstrated … of cardiac autonomic regulation
and mitochondrial function, … TNF production, and reduced PI3K and Akt activation which …

Age and ischemia differentially impact mitochondrial ultrastructure and function in a novel model of age-associated estrogen deficiency in the female rat heart

AM Garvin, NC Aurigemma, JL Hackenberger… - … -European Journal of …, 2017 - Springer
… AM, Korzick DH (2007) Estrogen deficiency decreases ischemic tolerance in the aged rat
heart: roles of PKCdelta, PKCepsilon, Akt, and GSK3beta. Am J Physiol Regul Integr Comp …

[HTML][HTML] Conditioning-induced cardioprotection: Aging as a confounding factor

PK Randhawa, A Bali, JK Virdi… - The Korean journal of …, 2018 - ncbi.nlm.nih.gov
… in ischemic tolerance with increasing age in isolated rat heartsfunction in the aged hearts
(21–22 months) suggesting that … Aging also tends to reduce ERK and AKT phosphorylation …

INTRUSION OF GLYCOGEN SYNTHASE KINASE-3β TO COPE VARIOUS CARDIAC DISORDERS AT MOLECULAR LEVEL.

VV Kumar, AT Mahmood, M Anup, SR Kumar… - Indian …, 2020 - search.ebscohost.com
… mediate mitochondrion function by binding with pI3K-Akt, pGC-… attenuated or lost in
hyperlipidemic rat heart is a new finding in … , significantly reduced the cardiac damage and …

Inhibition of programmed necrosis limits infarct size through altered mitochondrial and immune responses in the aged female rat heart

AM Garvin, MA Jackson… - … of Physiology-Heart and …, 2018 - journals.physiology.org
Estrogen deficiency decreases ischemic tolerance in the aged rat heart: roles of PKCdelta,
PKCepsilon, Akt, and GSK3beta. Am J Physiol Regul Integr Comp Physiol 292: R800–R809, …

Impact of age-associated estrogen deficiency on innate immune responses to myocardial ischemic injury in the female rat heart

MA Jackson - 2017 - etda.libraries.psu.edu
… women exhibit reduced tolerance to myocardial ischemia … the effects of age-associated
estrogen deficiency on innate … cardiac function relative to heart from aged, intact female rats, …

[HTML][HTML] … Geroscience: Inhibition of programmed necrosis limits infarct size through altered mitochondrial and immune responses in the aged female rat heart

AM Garvin, MA Jackson, DH Korzick - … Journal of Physiology-Heart …, 2018 - ncbi.nlm.nih.gov
Estrogen deficiency decreases ischemic tolerance in the aged rat heart: roles of PKCdelta,
PKCepsilon, Akt, and GSK3beta. Am J Physiol Regul Integr Comp Physiol 292: R800–R809, …

[HTML][HTML] Insulin directly stimulates mitochondrial glucose oxidation in the heart

QG Karwi, CS Wagg, TR Altamimi, GM Uddin… - Cardiovascular …, 2020 - Springer
… not influence cardiac function in the normal heart (Additional … polyols, pentoses, and AGEs
pathways occurs before glucose … reperfused rat heart is associated with decreased Akt activity …

[HTML][HTML] Pomegranate extract enhances endothelium-dependent coronary relaxation in isolated perfused hearts from spontaneously hypertensive ovariectomized rats

NTB Delgado, WN Rouver, LC Freitas-Lima… - Frontiers in …, 2017 - frontiersin.org
… to decrease reactive oxygen species (ROS). However, the role of sex hormones (mainly
estrogen… However, we not observed alterations after the treatment in total eNOS and total AKT as …

[PDF][PDF] Connexin 43 Contributes to Estrogen Protection against Oxidative Stress in Cortical Astrocytes

NK Kubelka - 2019 - unthsc-ir.tdl.org
… of homeostasis, and increases as a function of age. There are … the role of estradiol, DHT
and 3βdiol in regulating Cx43 function … in both heart tissue and astrocytes is decreased in the …